Track 22:Pancreatic Cancer

Sub tracks of Pancreatic Cancer

·  Adenocarcinoma (most common type, originating in the ducts of the pancreas)

·  Neuroendocrine Tumors (NETs, arise from hormone-producing cells)

·  Cystic Neoplasms (including serous and mucinous cystadenomas)

·  Acinar Cell Carcinoma (originating in enzyme-producing cells)

·  Pancreatoblastoma (rare, typically seen in children)

·  Solid Pseudopapillary Tumor (low-grade malignancy)

·  Metastatic Pancreatic Cancer (spread from other organs)

What is Pancreatic Cancer ?

• Pancreatic cancer is a type of cancer that begins in the tissues of the pancreas, a gland located behind the stomach. The pancreas plays a vital role in digestion and blood sugar regulation by producing digestive enzymes and hormones such as insulin and glucagon.
1. Types:
• Exocrine Tumors (most common): These affect the part of the pancreas that produces digestive enzymes, with adenocarcinoma being the most common subtype.
• Endocrine Tumors (rarer): These affect the hormone-producing islet cells and are sometimes called pancreatic neuroendocrine tumors (NETs).
2. Symptoms:
• Early stages often present no symptoms.
• Later stages may include:
• Abdominal or back pain
• Unintended weight loss
• Jaundice (yellowing of the skin and eyes)
• Loss of appetite
• Nausea or vomiting
• New-onset diabetes or worsening existing diabetes.
3. Risk Factors:
• Smoking
• Chronic pancreatitis
• Family history of pancreatic cancer or genetic syndromes
• Diabetes
• Obesity
• Age (most cases occur in people over 65).
4. Diagnosis:
• Imaging tests like CT, MRI, or endoscopic ultrasound
• Blood tests (e.g., CA 19-9 tumor marker)
• Biopsy of pancreatic tissue.
5. Treatment:
• Surgery (e.g., Whipple procedure)
• Chemotherapy
• Radiation therapy
• Targeted therapy or immunotherapy (in some cases).

Pancreatic cancer is known for its poor prognosis because it is often diagnosed at an advanced stage. However, early detection and treatment can improve outcomes.